hsTnT in renal impairment

Some additional information about hsTnT in patients with renal impairment (90% with eGFR 30-60mL/min) has been added to the Troponins in ACS page, derived from the following reference. Twerenbold, R, Wildi, K, Jaeger, C, et al. Optimal Cutoff Levels of More Sensitive Cardiac Troponin Assays for the Early Diagnosis of Myocardial Infarction in Patients With … Read more

New ‘Practice edition’ version available

We have just added a new filter for you to choose for Version 1 called ‘Practice edition’. Applying this filter keeps all the clinically immediately relevant information, and removes all of the following from view: ACEM curriculum descriptors ACEM learning objectives References All content that is not immediately relevant to clinical practice The content considered not immediately relevant to clinical practice … Read more

D dimer in pregnancy

The PE in special populations page has been updated with particular reference to d dimer levels during pregnancy. Some relevant references are: Greer, IA. Pregnancy Complicated by Venous Thrombosis. New England Journal of Medicine 2015;373(6):540-47. http://www.nejm.org/doi/full/10.1056/NEJMcp1407434. Kline, JA, Williams, GW, Hernandez-Nino, J. D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed. Clin Chem 2005;51(5):825-9. … Read more