0.45% Saline replacement volume formula for hypernatraemia

18/09/2026 by Bob Dunn

The Hypernatraemia page has been updated with a formula for calculating the volume of 0.45% saline required to replace TBW deficits.

Free water deficit formula

Hypernatraemia

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Associate Professor Robert Dunn

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Associate Professor Meredith Borland
Dr Deborah O'Brien
Dr Stuart Dilley
Dr Jennifer Brookes
Associate Professor Deborah Leach

Formula of the day

ETT (uncuffed) size in children < 1 year of age = (Age/4)+ 4

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It is good to know guidelines issued by prominent organizations. It is better to know evidence-based guidelines. It is best to know the evidence.

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Version 1
Version 2
I use both versions roughly equally

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