Adrenomedullin

The Hyperadrenalism page has been updated, including details about adrenomedullin and how it contributes to hypocalcaemia and haemodynamic instability in phaechromocytoma.

Clinical decision rules or clinical judgement?

The Clinical practice guidelines page has been updated with additional information about how often clinical decision rules in Emergency Medicine are compared with non-standardised practice, and how they fare when they are compared – and the news is not encouraging for guideline writers. Schriger, DL, Elder, JW, Cooper, RJ. Structured Clinical Decision Aids Are Seldom … Read more

NAC and HCO3 and IV contrast

Another nail in the coffin of CIN and it’s prevention. The Intravenous contrast page has been revised with removal of NAC and HCO3 as therapies to be considered for the prevention of a probably non-existent entity! Weisbord, SD, Gallagher, M, Jneid, H, et al. Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine. New England Journal … Read more