2-4 hour paracetamol levels

The Paracetamol page has been updated with information about the utility of a 2-4 hour paracetamol level in predicting subsequent potential toxicity. Yarema, MC, Green, JP, Sivilotti, MLA, et al. Can a serum acetaminophen concentration obtained less than 4 hours post-ingestion determine which patients do not require treatment with acetylcysteine? Clinical Toxicology 2016:1-7. 

Renal transplant survival

Some information about renal transplant survival and complications has been added to the Renal transplant page following the publication of Nieto, T, Inston, N, Cockwell, P. Renal transplantation in adults. BMJ 2016;355.

Beta HCG

The Pregnancy page has been updated with additional information about the accuracy of beta HCG in the diagnosis of pregnancy. Related changes have been made to the Ectopic pregnancy and Abnormal vaginal bleeding pages. 

Ankle sprain management

The Soft tissue injuries of the ankle and foot page has been updated with additional information about the management of ankle ligament injuries following the publication of the following article. Brison, RJ, Day, AG, Pelland, L, et al. Effect of early supervised physiotherapy on recovery from acute ankle sprain: randomised controlled trial. BMJ 2016;355:i5650.