NAC and paracetamol toxicity

[avatar user=”robjdunn” size=”original” align=”left” /] The Paracetamol page has been updated, including additional information regarding the Australasian treatment nomogram and how it compares to the nomogram used in the UK and Ireland.

More non ACS causes of troponin elevation

[avatar user=”robjdunn” size=”original” align=”left” /] Just when you thought troponin couldn’t be less specific for ACS, additional non ACS causes of elevated troponin have been added to the Non ACS causes of elevated troponin. It is telling in itself that there is a whole page on this subject! So if you do troponins on patients … Read more

Anti viral agents in influenza

The Influenza page has been updated to reflect the new evidence that indicates anti viral agents are less effective in the treatment of influenza than previously thought, reducing illness duration by only 14 – 17 hours and having little effect on rates of pneumonia or hospitalisation. Add these to the long list of drugs shown to be … Read more

Thrombolysis in intermediate risk PE

The Management of PE page has been updated to reflect the lack of benefit and excess of adverse effects in patients with intermediate risk PE (echocardiographic changes without hypotension) treated with thrombolysis compared to placebo which was reported in a trial just published in the NEJM.,

ACEM policy statement on thrombolysis in stroke

The Thrombolytic therapy in stroke page has been updated to incorporate ACEM’s revised statement on the subject updated in March 2014 that states: “ACEM recognises intravenous thrombolysis as a potentially beneficial intervention for acute ischaemic stroke. There is however, conflicting evidence such that the administration of stroke thrombolysis by ED staff is a controversial area and cannot currently … Read more