Phosphatidylethanol
A short segment on phosphatidylethanol testing has been added to the Ethanol page.
Updates
Andexanet for ICH in patients on DOACs
The Management of stroke page has been updated with some information about andexanet for the treatment of ICH in patients taking DOACs – there is insufficient evidence of benefit to recommend it at present. Future trials will need to be better designed than this one. Connolly, S. J., Sharma, M., Cohen, A. T. et al., … Read more
Neurosurgical transfer following trauma
Indications for transfer to a neurosurgical service following trauma have been added to the Management of head trauma page.
Metformin
The Other hypoglycaemic agents page has been updated with additional information about metformin, particularly regarding its relative lack of benefits compared to newer agents.
Semaglutide
The Other hypoglycaemic agents page has been updated with additional information about incretin mimetics/GLP1 agonists.
BP control in stroke
The Stroke management page has been updated with some revised recommendations for BP management following the publication of the following paper.Li, G., Lin, Y., Yang, J., et al., (2024). Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke. N Engl J Med, 390(20), 1862-1872. https://doi.org/10.1056/NEJMoa2314741
Thallium
The Non ferrous metals page has been updated with additional information about thallium.
Cobalt
The Non ferrous metals page has been updated with additional information about cobalt.
Arsenic
The Arsenic page has had a significant revision.
Lead
A number of minor updates and wording improvements have been made to the Lead page.
Management of drug induced seizures
A segment on management has been added to the Drug induced seizures page.
Hypophosphataemia
The Hypophosphataemia page has had a number of minor updates.
Features of pseudoseizures
The Assessment of isolated seizures page has been updated with additional features of pseudoseizures.
Features of true seizures
The Assessment of isolated seizures page has been updated with additional features of true seizures.
Bupropion toxicity
A new short segment on bupropion toxicity has been added to the Antidepressant toxicity page.
Endoscopy for poisoning
A short segment on endoscopy in the treatment of poisoning has been added to the Other methods of GIT decontamination page.
Investigation of pharmacobezoars
A short segment on the investigation or pharmacobezoars has been added to the Other methods of GIT decontamination page.
Pharmacobezoars
The segment on pharmacobezoars has been moved from the Pharmacokinetics page to the Other methods of GIT decontamination page.
Local anaesthesia
The Local anaesthesia page has had a number of updates.
Local anaesthesia key points
Key points have been added to the Local anaesthesia page.