Dunn RJ
The Cerebrovascular disease page has been updated with information about the equivalence of ticagrelor and aspirin for the prevention of stroke. Johnston, SC, Amarenco, P, Albers, GW, et al. Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack. New England Journal of Medicine;2016.
The Seizures page has been updated with a segment on seizures in pregnancy. Kinney, MO, Morrow, J. Epilepsy in pregnancy. BMJ 2016:i2880
A segment on Stiff person syndrome has been added to the Other movement disorders page.
The Cerebrovascular disease page has been updated with revised information about anticoagulation for patients with AF and end stage renal failure. Dahal, K, Kunwar, S, Rijal, J, et al. Stroke, Major Bleeding, and Mortality Outcomes in Warfarin Users With Atrial Fibrillation and Chronic Kidney Disease: A Meta-Analysis of Observational Studies. Chest 2016;149(4):951-59.
The Cerebrovascular disease page has been updated with revised information about the effectiveness of aspirin for stroke prevention in patients with TIA.
The segment on seizures and driving restrictions on the Management of isolated seizures page has been updated with reference to the Austroads: Assessing fitness to drive publication.
Some information about low dose (0.6mg/kg) IV tPA for the treatment of stroke has been added to the Thrombolytic therapy in stroke page. Anderson, CS, Robinson, T, Lindley, RI, et al. Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. N Engl J Med 2016.
Information regarding the position on ACEM on tPA for the treatment of stroke has been updated on the Thrombolytic therapy in stroke page.
The Platelet transfusion and Stroke management pages have been updated with information from the PATCH RCT published in Lancet that demonstrated an increase in disability and mortality from platelet transfusion in patients with supratentorial ICH on mostly aspirin, clopidogrel and/or dipyridamole. The exact mechanism for this is unclear. Baharoglu, MI, Cordonnier, C, Salman, RA-S, et al. … Read more
The Status epilepticus page has been updated including new information about the relative efficacy of different anti-convulsant agents.
A statement about how approximately 0.5% of patients with ICH may have transient neurological deficits has been added to the Intracerebral haemorrhage page.
The Phakomatoses page has been updated with a segment on Hypomelanosis of Ito.
A small segment on statin induced autoimmune myopathy has been added to the Neuropathies and myopathies page.
A short segment about deep brain stimulation and it’s potential adverse effects has been added to the Parkinson’s disease page.
A statement on the Investigation of suspected subarachnoid haemorrhage page has been clarified. The statement ‘aneurysm may infrequently be seen if > 5 mm diameter’, in relation to CT head has been corrected to ‘aneurysm may occasionally seen if > 5 mm diameter’. Thanks to Raymund for picking this up.
The Peripheral neuropathy page has been revised and updated following the recent JAMA article: Callaghan, BC, Price, RS, Feldman, EL. Distal Symmetric Polyneuropathy: A Review. JAMA 2015;314(20):2172-81.
A short segment on Charcot-Marie-Tooth disease has been added to the Peripheral neuropathy page.
A CT image of slit ventricles has been added to the Cerebral ventricular shunts page.
2 CT images of an arachnoid cyst have been added to the Cerebral tumours page.
The Assessment of facial weakness page has been updated with additional information about Bell’s palsy.