IV morphine vs IV paracetamol for sciatica

The Paracetamol page has been updated with information about the superiority of IV morphine over IV paracetamol (alone) in patients with sciatica. Serinken, M, Eken, C, Gungor, F, et al. Comparison of Intravenous Morphine Versus Paracetamol in Sciatica: A Randomized Placebo Controlled Trial. Academic Emergency Medicine 2016;23(6):674-78. 

Silent MI

The Clinical assessment of suspected ACS page has been updated with additional information about the incidence of silent ischaemia. Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 2016;133(22):2141-8.

sBP target for ICH is < 180mmHg

The Stroke management page has been revised to indicate that the target sBP value for the management of primary ICH is < 180mmHg and that reductions to 110-140mmHg appear to confer no additional benefit. Qureshi, AI, Palesch, YY, Barsan, WG, et al. Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. N Engl J Med 2016.

Ticagrelor for stroke prevention

The Cerebrovascular disease page has been updated with information about the equivalence of ticagrelor and aspirin for the prevention of stroke. Johnston, SC, Amarenco, P, Albers, GW, et al. Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack. New England Journal of Medicine;2016.

Sleeping, feeding and pooing in children

The Assessment of children page has been updated with additional information about the things little babies do best (see above) following the publication of the following review article: Goldstein, H, Tagg, A, Davis, T, et al. Baby steps: Understanding normal baby behaviour. Emerg Med Australas 2016;28(2):130-2.

Management of sepsis

The Assessment of sepsis and Management of sepsis pages have had a few minor modifications following the publication of the following review (which was more theoretical than clinical). Gotts, JE, Matthay, MA. Sepsis: pathophysiology and clinical management. BMJ 2016;353:i1585.

Drug induced psychosis

The Psychosis page has been revised including the addition of a table of features that may help differentiate drug induced psychosis from psychosis due to schizophrenia. Glasner-Edwards, S, Mooney, LJ. Methamphetamine psychosis: epidemiology and management. CNS Drugs 2014;28(12):1115-26.

Metacarpal fractures

The Hand injuries page has been updated with a revised section on metacarpal fracture management. In particular, the lack of evidence of benefit from surgical management of most metacarpal fractures has been re-emphasised. Neumeister, MW, Webb, K, McKenna, K. Non-surgical management of metacarpal fractures. Clin Plast Surg 2014;41(3):451-61.  Sletten, IN, Hellund, JC, Olsen, B, et … Read more

Ethnicity as a VTE risk factor

Ethnicity has been added as a risk factor for VTE to the Deep venous thrombosis page. Liao, S, McAnulty, K, Lim, C, et al. Ethnicity as an independent predictive factor for the results of CT pulmonary angiography and ultrasonography of the lower limbs. Internal Medicine Journal 2016:n/a-n/a. 

Falls

The Aging page has been updated with additional information about the epidemiology and assessment of falls, including the timed up and go test. Vieira, ER, Palmer, RC, Chaves, PH. Prevention of falls in older people living in the community. BMJ 2016;353:i1419.